KEYWORDS: MELD, End Stage Liver Disease, in-hospital mortality. CONCLUSION: Our study showed that MELD score is good predictor of in-hospital mortality in patients with end stage liver disease and best cut off value for MELD score is 22, above which the mortality rate is high. At cut off value more than 22, MELD score had 80% sensitivity with good predictive power. Based on distribution of MELD score in the study population we calculated the best cut-off point using Youden index (Sensitivity+specicity-1) to predict in-hospital mortality. The mean MELD score was higher in death group (28.5) compared to discharge group (22.03). Incidence of Hepatic encephalopathy and Hepatorenal syndrome was significantly higher (p value-0.038) in death group (70% and 30% resp.) compared to discharge group (40% and 23.3% resp.). The higher the number, the more likely you are to receive a liver from a deceased donor when an organ becomes available. Mean hospital stay was found to be 5.8 days in death group and 9.6 days in discharge group. The MELD score ranges from six to 40 and is based on results from several lab tests. For analysis, study population was divided into discharge group and death group. RESULTS: Out of 50 cirrhosis patients, 20 (40%) died within the hospital due to cirrhosis related complications. METHODS: It is an observational study involving 50 patients with end stage liver disease admitted to our hospital during the period of October 2012 to September 2014 who are fitting into the inclusion criteria. AIMS AND OBJECTIVES: To study the usefulness of MELD score for predicting inhospital mortality in patients with end stage liver disease. Although many studies have done on MELD score for prediction of 3 months and 6 months mortality in end stage liver disease, studies on MELD score for predicting in-hospital mortality is very sparse. Nowadays MELD score has been shown to be of much use in predicting outcome in end stage liver disease. Open cholecystectomy is associated with significantly more morbidity and mortality than laparoscopic cholecystectomy across all MELD groups.Īscites Cholecystectomy Cirrhosis MELD Model for end-stage liver disease NSQIP.Abstract : BACKGROUND/AIMS: Model for End stage Liver Disease (MELD) score was previously used for predicting the outcome in patients undergoing elective Trans-jugular Intrahepatic Porto-systemic Shunts (TIPS) and in patients undergoing liver transplantation. Patients with ascites have substantially worse outcomes across all MELD scores. The MELD score is an objective and easy to calculate scoring system that independently predicts postoperative morbidity and mortality in patients undergoing cholecystectomy. After adjustment, MELD score acted as a progressive and independent predictor of morbidity and mortality. Bivariate data analysis was performed and logistic regression modeling was conducted to calculate risk-adjusted 30-day outcomes.Ī total of 63,464 patients were included in the study. Patients were excluded if they had choledocholithiasis or preoperative dialysis. The American College of Surgeons National Surgical Quality Improvement Program database from 2005 to 2013 was used to study patients undergoing cholecystectomy. The magnitude of risk for patients undergoing cholecystectomy with high model for end-stage liver disease (MELD) scores is poorly understood.
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